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January 1, 2017Pharmacognosy MagazineOpen Access

Hepatoprotective effect of gallotannin-enriched extract isolated from gall on hydrogen peroxide-induced cytotoxicity in HepG2 cells

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Abstract

BACKGROUND: Gall (Galla Rhois [GR]) is known to have antibacterial, anti-inflammatory, antimetastatic, and anti-invasion activities and exert hepatoprotective effects. However, the hepatoprotective effects of gallotannin-enriched GR (GEGR) and their mechanisms have not yet been investigated. OBJECTIVE: ) was investigated. MATERIALS AND METHODS: exposure. RESULTS: + vehicle-treated group. CONCLUSION: in HepG2 cells through the induction of antioxidant conditions. SUMMARY: : Hydrogen peroxide; MMP: Metallopeptidase; MTT: 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; ROS: Reactive oxygen species; UV-Vis: Ultraviolet-visible.

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Jun Go (2017) studied this question.

synapsesocial.com/papers/6aa805e3632e33bdd69f19f1 https://doi.org/10.4103/pm.pm_424_15

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