Letters15 July 2014Prevention of Diabetes With Mediterranean DietsEran Kopel, MD, MPH, Yechezkel Sidi, MD, and Shaye Kivity, MDEran Kopel, MD, MPHFrom Chaim Sheba Medical Center, Tel Hashomer, Israel., Yechezkel Sidi, MDFrom Chaim Sheba Medical Center, Tel Hashomer, Israel., and Shaye Kivity, MDFrom Chaim Sheba Medical Center, Tel Hashomer, Israel.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITORWe believe that Salas-Salvadó and colleagues' subgroup analysis (1), which found that a Mediterranean diet enriched with extra-virgin olive oil reduces risk for diabetes, is methodologically flawed. During the study, more participants were lost to follow-up in the low-fat diet control group (10.5%) than in the Mediterranean diet groups supplemented with olive oil (4.1%) or mixed nuts (6.9%). The authors state that participants in the control group "who withdrew had a worse cardiovascular risk profile at baseline than those who remained in the study." This fact indicates that the entire control group in the subgroup analysis had ...References1. Salas-Salvadó J, Bulló M, Estruch R, Ros E, Covas MI, Ibarrola-Jurado N, et al. Prevention of diabetes with Mediterranean diets: a subgroup analysis of a randomized trial. Ann Intern Med. 2014;160:1-10. [PMID: 24573661] LinkGoogle Scholar2. Hu FB, Stampfer MJ, Haffner SM, Solomon CG, Willett WC, Manson JE. Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetes. Diabetes Care. 2002;25:1129-34. [PMID: 12087009] CrossrefMedlineGoogle Scholar3. Kopel E, Sidi Y, Kivity S. Mediterranean diet for primary prevention of cardiovascular disease [Letter]. N Engl J Med. 2013;369:672. [PMID: 23944308] CrossrefMedlineGoogle Scholar4. Fine JP, Gray RJ. A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc. 1999;94:496-509. CrossrefGoogle Scholar5. Andersen PK, Geskus RB, de Witte T, Putter H. Competing risks in epidemiology: possibilities and pitfalls. Int J Epidemiol. 2012;41:861-70. [PMID: 22253319] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Chaim Sheba Medical Center, Tel Hashomer, Israel.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0108. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrevention of Diabetes With Mediterranean Diets Jordi Salas-Salvadó , Mònica Bulló , Ramón Estruch , Emilio Ros , Maria-Isabel Covas , Núria Ibarrola-Jurado , Dolores Corella , Fernando Arós , Enrique Gómez-Gracia , Valentina Ruiz-Gutiérrez , Dora Romaguera , José Lapetra , Rosa Maria Lamuela-Raventós , Lluís Serra-Majem , Xavier Pintó , Josep Basora , Miguel Angel Muñoz , José V. Sorlí , and Miguel A. Martínez-González Prevention of Diabetes With Mediterranean Diets Miguel A. Martínez-González , Ramón Estruch , Dolores Corella , Emilio Ros , and Jordi Salas-Salvadó Prevention of Diabetes With Mediterranean Diets Miguel A. Martínez-González , Ramón Estruch , Dolores Corella , Emilio Ros , and Jordi Salas-Salvadó Metrics Cited byEffect of Dietary Strategies on Respiratory Quotient and Its Association with Clinical Parameters and Organ Fat Loss: A Randomized Controlled TrialThe PREDIMED trial, Mediterranean diet and health outcomes: How strong is the evidence?Fruit Consumption and Cardiovascular Disease in China 15 July 2014Volume 161, Issue 2Page: 157KeywordsConflicts of interestDiabetes preventionDietDisclosureHyperinsulinemiaMorbidityOils ePublished: 15 July 2014 Issue Published: 15 July 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
No takes yet. Share an insight, caveat, or question.
Kopel et al. (2014) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: