Bilateral nephrectomy is a rarely used approach to control refractory hypertension in patients with anuric end-stage renal disease (ESRD) who already require dialysis. This procedure results in complete dependence on hemo- or peritoneal dialysis to maintain metabolic homeostasis and has fallen out of favor given advancements in anti-hypertensive pharmacotherapy. Given the rarity of this management decision, there is a paucity of scientific literature regarding how the absence of kidneys impacts childbearing.
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Anna et al. (2020) studied this question.
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