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August 1, 2002Journal of Medicinal ChemistryOpen Access

Discovery of Further Pyrrolidine trans -Lactams as Inhibitors of Human Neutrophil Elastase (HNE) with Potential as Development Candidates and the Crystal Structure of HNE Complexed with an Inhibitor (GW475151)

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Authors

SMSimon J. F. MacdonaldUniversity of HertfordshireMDMichael D. DowleUniversity of HertfordshireLHLee A. HarrisonGlaxoSmithKline (United Kingdom)

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Macdonald et al. (2002) studied this question.

synapsesocial.com/papers/6aa81fe2d8938d5606b184c7https://doi.org/10.1021/jm020881f
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