Key result
Prostaglandin analogues exhibit specific structure-activity relationships that influence their ocular hypotensive efficacy.
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Informs rational design of next-generation ocular hypotensives; leaves open clinical translation pending prospective trials.
(1993). Overview: Structure-Activity Relationships of Prostaglandin Analogues as Ocular Hypotensive Agents. Current Opinion on Therapeutic Patents: Vol. 3, No. 6, pp. 781-795.
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Resul et al. (1993) studied this question. Prostaglandin analogues demonstrate specific structure-activity relationships that influence their efficacy as ocular hypotensive agents.
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