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While typical presentations of colorectal cancer include gastrointestinal symptoms such as changes in bowel habits, anemia, and hematochezia, it can also present atypically, including direct invasion of adjacent structures such as the abdominal wall. This report details a rare case of cecal adenocarcinoma manifesting as rapidly progressive abdominal wall necrosis in a 43-year-old woman, highlighting the diagnostic challenge in such unusual presentations. The case underscores the importance of maintaining a high index of suspicion for underlying malignancy in atypical clinical scenarios and illustrates the complexity of balancing wound care, infection control, and oncologic management to optimize patient outcomes.
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Tickal et al. (2025) studied this question.
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