Why the study?
Does a preoperative DLCO <70% predicted predict postoperative cardiopulmonary complications in patients undergoing pneumonectomy for lung cancer?
Population
151 patients undergoing pneumonectomy for lung cancer, mean age 61 years, 66% male, treated at Vancouver…
Comparison
Preoperative diffusing capacity for carbon… vs Preoperative DLCO ≥ 70% predicted
Design
Cohort
Follow-up
30 days
Key result
A preoperative DLCO <70% predicted was associated with a 94% postoperative complication rate following pneumonectomy, compared to 27% in patients with a DLCO ≥70% predicted.
Authors
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May refine preoperative risk stratification for pneumonectomy; leaves open whether DLCO thresholds should alter surgical decisions pending validation.
Cohort (n=151)
No
Does a preoperative DLCO <70% predicted predict postoperative cardiopulmonary complications in patients undergoing pneumonectomy for lung cancer?
Absolute Event Rate: 94% vs 27%
A preoperative DLCO of less than 70% predicted is a strong functional predictor of postoperative cardiopulmonary complications in patients undergoing pneumonectomy.
Jeng‐Shing Wang (2003) conducted a cohort in Lung cancer requiring pneumonectomy (n=151). DLCO < 70% predicted vs. DLCO ≥ 70% predicted was evaluated on Postoperative complications within 30 days. A preoperative DLCO <70% predicted was associated with a 94% postoperative complication rate following pneumonectomy, compared to 27% in patients with a DLCO ≥70% predicted.
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