Key result
Surgical reoperation for aortic valve graft infection is linked to ~67% lower early mortality versus medical treatment.
Why the study?
Infection of aortic valve graft conduits carries notable morbidity and mortality, and medical and surgical management strategies crucially influence patient outcomes.
Does surgical reoperation improve survival compared to conservative medical treatment in patients with composite aortic valve graft infection?
Cohort (n=30)
No
Does surgical reoperation improve survival compared to conservative medical treatment in patients with composite aortic valve graft infection?
Absolute Event Rate: 10% vs 30%
Surgical reoperation for composite aortic valve graft infection is associated with significantly better long-term survival compared to conservative medical management.
Supports surgical reoperation over medical therapy for composite aortic valve graft infection; leaves open need for randomized confirmation before changing practice.
Background The Infection of aortic valve graft conduit is still burdened by notable morbidity and mortality. Medical and surgical strategies play a crucial role in patient outcome and vary depending on infection extend into adjacent cardiac structures, systemic spread and micro-organism involved. Methods In this retrospective study, we report our experience in the management of thirty consecutive patients admitted to our centre with composite aortic valve graft infection during the period 2008-2018. We review the early and mid-term outcomes of patients who underwent a reoperation or received a conservative medical treatment. Results Twenty patients underwent redo surgery with an early mortality of 10% and a survival of 83% at 7-year follow-up. Ten patients were treated medically and experienced an early mortality of 30% and a mid-term survival of 33%. Conclusion A surgical reoperation, despite a non-negligible perioperative risk, is the only radical treatment able to provide a good survival also in patients with complicated infective endocarditis.
No takes yet. Share an insight, caveat, or question.
Olevano et al. (2020) conducted a cohort in Composite aortic valve graft infection (n=30). Surgical reoperation vs. Conservative medical treatment was evaluated on Early mortality. Surgical reoperation for composite aortic valve graft infection yielded 10% early mortality and 83% 7-year survival, versus 30% early mortality and 33% mid-term survival with medical treatment.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: