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September 3, 2012PROGRESS IN BIOCHEMISTRY AND BIOPHYSICSOpen Access

Molecular Regulaion of BACE1 and Its Function at The Early Onset of Alzheimer′s Disease

Tan Wang Xiulian Sun

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Abstract

A茁 isthemajorcomponentsofamyloidplaquedepositioninthebrain,andisconsideredtobethe initiatingfactorforthepathogenesisofAlzheimer'sdisease(AD).茁-amyloidprecursorproteincleavingenzyme1 (BACE1)isoneoftheimportantenzymesintheA 茁production.Theprocessofmaturationandexpressionof

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Wang et al. (2012) studied this question.

synapsesocial.com/papers/6aa86a0e355c6aac221e951c https://doi.org/10.3724/sp.j.1206.2012.00217

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