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January 1, 1997Archiv der Pharmazie

Structure‐Activity Relationship Studies of CNS Agents, Part 32[1]: Effect of Structural Modifications in 1‐Arylpiperazine Derivatives on α1‐Adrenoreceptor Affinity

Maria J. Mokrosz Maria H. Paluchowska Sijka Charakchieva‐Minol Anna Bień

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Abstract

The alpha(1)-adrenergic and 5-HT1A serotonergic receptor affinities of a series of 1-arylpiperazines are presented. The role of the spacer and the influence of the terminal substituents on the alpha(1)-adrenoreceptor affinity and the 5-HT1A/alpha(1) receptor selectivity are discussed.

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Mokrosz et al. (1997) studied this question.

synapsesocial.com/papers/6aa887107e9c410215429093 https://doi.org/10.1002/ardp.19973300605

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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