Key result
SOFA and APACHE IVa scores exhibit prognostic bias with worse mortality discrimination in non-English speakers.
Why the study?
Although illness severity scoring systems are widely used in ICUs, their potential bias across different age, sex, and primary language groups has not been well studied.
Do SOFA and APACHE IVa scores exhibit prognostic bias across age, sex, and primary language groups in ICU patients?
Observational (n=196,310)
Yes
Do SOFA and APACHE IVa scores exhibit prognostic bias across age, sex, and primary language groups in ICU patients?
Critical illness severity scores like SOFA and APACHE IVa exhibit prognostic bias across age, sex, and primary language groups, suggesting caution when using them for decision-making in diverse populations.
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Liu et al. (2024) conducted an observational in Critical illness (n=196,310). SOFA and APACHE IVa scores was evaluated on Hospital mortality (p=< 0.0001). SOFA and APACHE IVa scores exhibited prognostic bias for hospital mortality, with worse discrimination in non-English speakers compared to English speakers (AUROC 0.726 vs. 0.783, p < 0.0001).
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