Key result
Minimally invasive MVR linked to ~33% fewer early complications vs median sternotomy in severe COPD.
Why the study?
Minimally invasive valve surgery is considered more beneficial than routine median sternotomy in patients with severe COPD, but their early outcomes needed direct comparison in isolated MVR.
Does minimally invasive mitral valve replacement improve early postoperative outcomes compared to median sternotomy in patients with severe COPD?
Cohort (n=100)
Does minimally invasive mitral valve replacement improve early postoperative outcomes compared to median sternotomy in patients with severe COPD?
Absolute Event Rate: 16% vs 24%
p-value: p=<0.05
Minimally invasive mitral valve replacement is associated with fewer early complications, shorter mechanical ventilation time, and reduced hospital stays compared to median sternotomy in patients with severe COPD.
Minimally invasive MVR may shorten recovery in severe COPD; Level 5 data leaves open whether it should replace sternotomy.
Background: Minimally invasive valve surgery is considered much more beneficial than routine median sternotomy in patients undergoing open heart surgery with sever chronic obstructive pulmonary disease (COPD). Objective: To compare between early outcomes of minimally invasive versus routine median sternotomy in patients with severe COPD undergoing isolated mitral valve replacement (MVR). Patients and Methods: 100 patients with severe COPD between October 2016 and September 2019 underwent isolated MVR. Patients were divided into 2 groups: Group (A): 50 patients underwent surgery via minimally invasive approach and group (B): 50 patients underwent surgery via median sternotomy. Early postoperative complications, Intensive Care Unit stay and total hospital stay were compared in both groups. Results: The mean age was 60 ± 9 years for Group (A) and 61 ± 10 years for Group (B), (P = 0.29). Combined postoperative complications were significantly lower in Group (A) [8 (16%) versus 12 (24%), P < 0.05]. The median postoperative mechanical ventilation time was 10 hours in group (A) versus 22 hours in group (B) (P < 0.05). The median ICU stay in group (A) was 1.5 days versus 3 days in group (B) (P < 0.05). The median length of total hospital stay was 7 days in group (A) versus 13 days in group (B) (P < 0.05). The overall hospital mortality was 2 patients (4%) in group (A) versus 1 patient (2%) in group (B) P < 0.05. Conclusion: Minimally invasive had better early outcome than routine median sternotomy in patients with severe COPD undergoing MVR and should be considered as a good option in these patients.
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Mahmoud et al. (2021) conducted a cohort in Severe chronic obstructive pulmonary disease (COPD) requiring isolated mitral valve replacement (n=100). Minimally invasive mitral valve replacement vs. Routine median sternotomy was evaluated on Combined postoperative complications (p=<0.05). Minimally invasive mitral valve replacement in patients with severe COPD reduced combined early postoperative complications compared to median sternotomy (16% vs 24%, P<0.05).
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