Key result
Computational fluid dynamics simulation demonstrated that the presence of a thrombus inside a stenotic vein causes complex flow patterns, including low velocity and high vorticity, which may promote further thrombus growth.
Why the study?
Visualizing thrombus presence in veins via ultrasound is challenging due to image noise, making evaluation of vessel condition difficult.
Answers are grounded in this paper and cite their sources.
CFD simulation demonstrates that low blood velocity regions at the vein valve cusps and leaflet bases are probable locations for thrombus development.
Blood velocity is expected to be as a parameter for detecting abnormality of blood such as the existence of thrombus. Proper blood flow in veins is important to ensure effective return of deoxygenated blood to the heart. However, it is much challenging to recognize the vessel condition due to the inability to visualize the thrombus presence in the vessel. The presence of noise in the image obtained from ultrasound scanning is one of the obstructions in recognizing it. Considering the difficulty, this study aims to assess the velocity and vorticity at the vein valve region using Computational Fluid Dynamics (CFD) method. The velocity of blood and the size of valve orifice are considered important parameters in designing the vein since the stenosis and irregularities of velocity in blood vessels are known as the risk factors for thrombus formation. From the simulation, the velocity contour plot of the blood flow can be visualized clearly. The blood distribution was presented using velocity profile while the fluid particles movement was shown by the velocity vector. The low blood velocity clearly shows the low velocity region which reside at the cusps area and at the beginning of the valve leaflets. Therefore, the present study is able to visualize and evaluate the probable location of thrombus development in the blood vessel.
No takes yet. Share an insight, caveat, or question.
Ibrahim et al. (2021) studied Deep vein thrombosis. Thrombus presence (1 mm and 3 mm sizes) and varying valve orifice sizes vs. No thrombus and normal valve orifice was evaluated on Blood flow velocity, velocity profile, velocity vector, and vorticity. Computational fluid dynamics simulation demonstrated that the presence of a thrombus inside a stenotic vein causes complex flow patterns, including low velocity and high vorticity, which may promote further thrombus growth.
Synapse has enriched 10 related papers. Consider them for comparative context: