Predictive factors in the treatment of Pseudo-Acanthosis Nigricans by Fractional Carbon Dioxide Laser and Glycolic Acid Peel

BACKGROUND: Acanthosis nigricans is a common dermatological disorder characterized by hyperpigmented and hyperkeratotic velvety skin lesions. It can be a manifestation of systemic disease. OBJECTIVE: This study aims to evaluate the clinical and laboratory predictive factors in the treatment of pseudo-acanthosis nigricans. PATIENTS AND METHODS: This study included 20 patients with pseudo-acanthosis nigricans from the outpatient clinic. All cases were subjected to fractional CO2 laser on the right side of the neck and glycolic acid peel 70% on the left side of the neck. Each patient was followed up for three and half months. RESULTS: There was an overall improvement in area index, severity, and texture in the neck of cases with pseudo-acanthosis nigricans treated with fractional CO2 laser or Glycolic acid peel. CONCLUSION: There was no statistical significance when comparing the effect of laser or peeling on different age groups and obese or overweight cases.