Key result
Surgical aortic valve replacement with a RESILIA tissue bioprosthesis demonstrated favorable safety, with 4.5% overall mortality and no structural valve deterioration at 3-year follow-up.
Why the study?
Bioprosthetic surgical aortic valve replacement is increasingly adopted in younger patients, prompting the need to assess the mid-term clinical performance of the prosthesis.
What are the midterm procedural and clinical outcomes of surgical aortic valve replacement using a bioprosthetic valve with RESILIA tissue?
Observational (n=154)
No
What are the midterm procedural and clinical outcomes of surgical aortic valve replacement using a bioprosthetic valve with RESILIA tissue?
SAVR with a RESILIA tissue bioprosthetic valve demonstrates favorable hemodynamics and safety with no structural valve deterioration at 3-year follow-up.
BACKGROUND AND AIM: Bioprosthetic surgical aortic valve replacement (SAVR) is increasingly adopted in younger patients. We aimed to analyze mid-term follow-up data after SAVR to assess the performance of the prosthesis. METHODS: Data were collected from a single-center series of 154 patients, who underwent SAVR with a bioprosthetic heart valve with the RESILIA tissue at our Heart Centre in Siegburg. All procedural and midterm patient outcomes were documented. RESULTS: Patients had a mean age of 56.8 ± 9.9 years, 35.7% were female, and the mean logistic European system for cardiac operative risk evaluation (EuroSCORE) was 3.4 ± 3.6%. Diabetes (12.3%), atrial fibrillation (10.4%), and chronic obstructive pulmonary disease (COPD) (5.8%) were common comorbidities. The mean surgery duration was 163.8 ± 73.4 min, with the 23 mm (34.4%) and 25 mm (33.8%) heart valves being most frequently implanted. At 3-year follow-up, mean pressure gradient was 13.9 ± 5.9 mmHg, peak gradient was 23.6 ± 7.7 mmHg, and effective orifice area (EOA) was 1.9 ± 0.4 cm². No patient died during the operation, 3 (2.1%) patients within 30 days, and 4 (2.7%) thereafter with an overall mortality of n = 7. Of the surviving patients, 97.8% were in New York Heart Association (NYHA) class I/II and none had structural valve deterioration (SVD). CONCLUSION: Results of our single-center study indicate favorable procedural outcomes. The safety outcomes confirm preliminary earlier results of this novel bioprosthesis but include more patients and a longer midterm follow-up.
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Ahmad et al. (2022) conducted an observational in Aortic valve disease requiring surgical aortic valve replacement (n=154). Bioprosthetic surgical aortic valve replacement with RESILIA tissue was evaluated on Overall mortality. Surgical aortic valve replacement with a RESILIA tissue bioprosthesis demonstrated favorable safety, with 4.5% overall mortality and no structural valve deterioration at 3-year follow-up.
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