Key result
EBT correlates with TTE but yields an anatomically larger AVA by ~0.51 cm2.
Why the study?
Does electron beam computed tomography (EBT) correlate with transthoracic echocardiography (TTE) for determining aortic valve area in patients with valvular aortic stenosis?
Cross-Sectional (n=30)
Single-blind
No
Does electron beam computed tomography (EBT) correlate with transthoracic echocardiography (TTE) for determining aortic valve area in patients with valvular aortic stenosis?
Mean Difference: 0.51
p-value: p=<0.01
EBT is a valuable non-invasive method for measuring anatomical aortic valve area, which correlates with but is systematically larger than the functional area calculated by TTE.
Caution advised comparing EBT and TTE aortic valve areas due to systematic differences; leaves open optimal non-invasive assessment strategies.
The purpose of this study was to compare electron beam computed tomography (EBT) with transthoracic echocardiography (TTE) in determining aortic valve area (AVA). Thirty patients (9 females, 21 males) underwent a contrast-enhanced EBT scan (e-Speed, GE, San Francisco, CA, USA) and TTE within 17 +/- 12 days. In end-inspiratory breath hold, a prospectively ecg-triggered scan was acquired with a beam speed of 50-100 ms, a collimation of 2 x 1.5 mm and an increment of 3.0 mm. The AVA was measured with planimetry. A complete TTE study was performed in all patients, and the AVA was computed using the continuity equation. There was close correlation between AVA measured with EBT and AVA assessed with TTE (r = 0.60, P < 0.01). The AVA measured with EBT was 0.51 +/- 0.46 cm(2 )larger than the AVA calculated with TTE measurements. EBT appeared to be a valuable non-invasive method to measure the AVA. EBT measures the anatomical AVA, while with TTE the functional AVA is calculated, which explains the difference in results between the methods.
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Piers et al. (2007) conducted a cross-sectional in Valvular aortic stenosis (n=30). Electron beam computed tomography (EBT) vs. Transthoracic echocardiography (TTE) was evaluated on Aortic valve area (AVA) (MD 0.51, p=<0.01). Electron beam computed tomography measurements of aortic valve area correlated significantly with transthoracic echocardiography (r = 0.60, P < 0.01), but yielded an anatomically larger area by an average of 0.51 cm2.
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