Design
Review
Key result
TRPV4 channels are strategically localized to sense hemodynamic changes and contribute to the regulation of vascular tone through smooth muscle cell hyperpolarization and vasodilation.
Authors
Loading...
May guide vascular research; leaves open TRPV4-targeted therapies pending prospective validation.
This review highlights the critical role of TRPV4 channels in sensing hemodynamic changes and regulating vascular tone through smooth muscle cell hyperpolarization and vasodilation.
Filosa et al. (2012) conducted a review in Vascular tone regulation. TRPV4 channels was evaluated. TRPV4 channels are strategically localized to sense hemodynamic changes and contribute to the regulation of vascular tone through smooth muscle cell hyperpolarization and vasodilation.