Key result
Mild-to-moderate COVID-19 is linked to relative bradycardia, increasing pulse ~7 beats/min per degree Celsius.
Why the study?
Coronavirus disease is reported to affect the cardiovascular system, prompting examination of relative bradycardia in mild-to-moderate cases.
Observational (n=54)
No
Relative bradycardia is a common clinical sign in patients with mild-to-moderate COVID-19, which may aid clinicians in diagnosing the disease.
May support relative bradycardia in COVID-19 differentials; hypothesis-generating and requires prospective validation before clinical adoption.
Coronavirus disease is reported to affect the cardiovascular system. We showed that relative bradycardia was a common characteristic for 54 patients with PCR-confirmed mild-to-moderate coronavirus disease in Japan. This clinical sign could help clinicians to diagnose this disease.
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Ikeuchi et al. (2020) conducted an observational in Mild-to-moderate COVID-19 (n=54). 1°C increase in body temperature was evaluated on Change in pulse rate per 1°C increase in body temperature (7.37 beats/min, 95% CI 5.92-8.82). In patients with mild-to-moderate COVID-19, the predicted change in pulse rate was 7.37 beats/min for each 1°C increase in body temperature, demonstrating relative bradycardia.
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