Key result
Hepatic angiosarcoma presents with vague symptoms and progresses rapidly to death within 7 months.
Why the study?
Hepatic angiosarcoma is a rare and exceptionally deadly primary liver tumor with nonspecific initial presentation and no associated tumor markers, often diagnosed late.
Case Report (n=1)
No
Highlights the diagnostic challenge of hepatic angiosarcoma due to nonspecific initial presentation and lack of tumor markers.
Alerts clinicians to hepatic angiosarcoma in vague presentations with nondiagnostic biopsy; leaves open need for better diagnostic strategies in prospective studies.
Hepatic angiosarcoma (HA) accounts for 2% of primary liver tumors. Though rare, it is exceptionally deadly. The initial presentation of HA is nonspecific and no tumor markers have been associated with it. In general, liver function is maintained until later stages of the disease, often leading to diagnosis once the disease is already advanced or metastatic. In this report, we present the case of a 54-year-old male whose vague symptoms and non-diagnostic liver biopsy delayed the diagnosis of a rapidly progressing HA.
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Averbukh et al. (2018) conducted a case report in Hepatic angiosarcoma (n=1). Chemotherapy (gemcitabine and vinorelbine) was evaluated. A 54-year-old male with vague symptoms and an initially non-diagnostic liver biopsy was diagnosed with rapidly progressing hepatic angiosarcoma and expired seven months after diagnosis.
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