This case report concerns a woman of 54 who died from a rapidly progressive lymphosarcoma-cell leukaemia with the terminal complication of toxoplasmosis. The grossly atypical lymphosarcoma cells were shown to form rosettes with sheep erythrocytes but were incapable of responding to stimulation with phytohaemagglutinin. They thus had the functional characteristics of abnormal T-cells. The proportion of immunoglobulin-bearing lymphocytes was greatly reduced.
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Burchardt et al. (1975) studied this question.
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