Mechanistic study reveals that the Aer2 tri-HAMP region modulates receptor signaling and polar clustering in Pseudomonas aeruginosa, highlighting novel functions for poly-HAMP arrays.
-dependent signaling from the PAS sensing domain and that HAMP1 controls the formation of Aer2-containing polar foci in P. aeruginosa. Both of these are newly recognized roles for HAMP domains that may be applicable to other non-signal-transducing HAMP domains and poly-HAMP chains.
No takes yet. Share an insight, caveat, or question.
Anaya et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: