⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

August 1, 2025Pediatric Allergy and Immunology

Safety and feasibility of very‐low‐dose egg challenge for children with severe allergies

Noriyuki Yanagida Sakura Sato Kyohei Takahashi Akira Kawai Yoko Miura Ken‐ichi Nagakura Yuki Ejiri Kiyotake Ogura Motohiro Ebisawa

View at Publisher

Ask AI

Bookmark

Share

Key Points

To assess the safety and feasibility of conducting very-low-dose oral food challenges in children diagnosed with severe egg allergies.
Administered very-low-dose egg challenges in a monitored pediatric cohort with severe allergic history to evaluate challenge safety and practical execution.
Numeric efficacy and adverse event rates are omitted in the provided text.
The clinical protocol focuses on establishing threshold safety while minimizing severe systemic hypersensitivity events.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Ask your own question…

Implication

Clinical evaluation examines very-low-dose egg challenges in severely allergic children, indicating potential options for safer threshold testing.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Yanagida et al. (2025) studied this question.

synapsesocial.com/papers/6aa8df8ff1edd38da570ee11 https://doi.org/10.1111/pai.70169

View at Publisher

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Safe egg yolk consumption after a negative result for low‐dose egg oral food challengeCohort Study · 2020 · 10 citations
2Efficacy of very-low-dose oral food challenge in children with severe hen egg allergy: A retrospective, single-center case series2024 · 5 citations
3Fixed Very‐Low‐Dose Oral Immunotherapy in Infants and Toddlers With Low‐Threshold Egg, Milk or Wheat Allergy: A Prospective Cohort StudyCohort Study · 2026
4Real-world evaluation of adherence and safety of tiny-dose heated egg white powder based on the Prevention of Egg Allergy with Tiny Intake study: A caregiver surveyOriginal Research · 2026
5Efficacy and safety of a 4-step versus a 5-step egg ladder in children with IgE-mediated hen's egg protein allergy: protocol for an open-label randomized controlled trial2025 · 2 citations

Comparative Safety of Baked Egg, Egg Yolk, and Egg White in Young Children with Egg Allergy2025
Reducing the need for food allergen challenges in young children: a comparison of in vitro with in vivo tests2001
Validity of specific IgE antibodies in children with egg allergy2001
When cure is not enough: Parental anxiety, depression, and caregiver burden after HSCT for inborn errors of immunityPediatric Allergy and Immunology · 2026
Inhibition studies to direct oral immunotherapy in walnut‐hazelnut co‐allergic patients (nut CRACKER study)Pediatric Allergy and Immunology · 2026

More from Pediatric Allergy and Immunology

More from National Sagamihara Hospital