Secondary metabolites from marine-derived fungus Aspergillus sp. SF6390 and their biological effects

This is the authors' abstract. We don't add key points for this paper.

A new secondary metabolite, aspernigrin F (1), possessing a unique 2-benzylpyridine-4-one substructure along with six known fungal metabolites were isolated from marine-derived fungus Aspergillus sp. SF6390. The chemical structures of all metabolites were mainly determined by analysing 1D, 2D NMR and HRESI-MS data. The isolated metabolites were assayed for their anti-inflammatory and cytoprotective effects in various cell lines such as RAW264.7 macrophages, BV2 microglia cells, hippocampal HT22, and HepG2 cell lines.