The electrospun bead-rich nanofibers are collected by biochemically active counterionic hydrosol; thus the core–shell structured microcapsules are fabricated with a positively-to-negatively charged shell. This novel one-step method of generating microcapsules can be applied to a variety of drug-delivery formulations only by filtering, diluting, or concentrating the hydrosol.
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Ye et al. (2010) studied this question.
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