Abrupt global-ocean anoxia during the Late Ordovician–early Silurian detected using uranium isotopes of marine carbonates

C positive excursion, but lasted longer indicating that controls on the C budget were partially decoupled from global-ocean redox trends. U cycle modeling suggests that there was a ∼15% increase in anoxic seafloor area and ∼80% of seawater U was sequestered into anoxic sediments during the HOAE. Unlike other ocean anoxic events (OAE), the HOAE occurred during peak and waning icehouse conditions rather than during greenhouse climates. We interpret that anoxia was driven by global cooling, which reorganized thermohaline circulation, decreased deep-ocean ventilation, enhanced nutrient fluxes, stimulated productivity, which lead to expanded oxygen minimum zones.