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August 11, 2000Biochemistry

Operator DNA Sequence Variation Enhances High Affinity Binding by Hinge Helix Mutants of Lactose Repressor Protein

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Authors

CFCatherine M. FalconKMKathleen S. MatthewsUniversity Health Network

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Falcon et al. (2000) studied this question.

synapsesocial.com/papers/6aa8faf35ea9f476fd6bfe29https://doi.org/10.1021/bi000924z
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Structural studies of protein–nucleic acid interaction: the sources of sequence-specific binding1990 · 509 citations
  2. 2Lac Repressor1973 · 216 citations
  3. 3Structural Studies of Protein-Nucleic Acid Interactions1983 · 99 citations
  4. 4Glycine Insertion in the Hinge Region of Lactose Repressor Protein Alters DNA Binding1999 · 53 citations
  5. 5Designed Disulfide between N-terminal Domains of Lactose Repressor Disrupts Allosteric Linkage1997 · 30 citations