NHC pumping on your stereo: A general N-heterocyclic carbene (NHC) catalyzed methodology for insertion of CO2 into N-tosyl aziridines giving 3,5-disubstituted and 3,4,5-trisubstituted oxazolidin-2-ones is developed. This method is also applied for the stereoselective synthesis of (4R,5R)-4-methyl-5-phenyloxazolidin-2-one.
No takes yet. Share an insight, caveat, or question.
Seayad et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: