For almost two decades we have followed a kindred with the familial, atypical, multiple-mole melanoma (FAMMM) syndrome. We first evaluated the proband's 14-year-old daughter when she was age 5 years. We documented the evolution, both clinically and histologically, of the FAMMM phenotype in this girl for eight years.
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Lynch et al. (1985) studied this question.
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