Key result
UK clinicians find RCOG VTE scoring complex and ~43% overestimate VTE death risk.
Why the study?
Despite guidelines recommending timely risk assessment and thromboprophylaxis, pregnancy-related VTE maternal mortality in the UK remains at mid-1990s levels, prompting a survey to inform a guideline update.
Cross-Sectional
Yes
UK clinicians find current pregnancy VTE risk assessment guidelines complex and often overestimate VTE risks while requiring a disproportionately high risk threshold to prescribe thromboprophylaxis.
Clinicians may need simpler VTE tools or education to curb overestimation; leaves open whether revisions improve appropriate thromboprophylaxis in pregnancy.
Venous thromboembolism (VTE) is the leading cause of maternal mortality in the UK during and within 6 weeks of the end of pregnancy. Despite considerable national attention to the importance of VTE-related morbidity and mortality during pregnancy and postpartum, and Royal College of Obstetricians and Gynaecologists (RCOG) guidelines that recommend timely VTE risk assessment and thromboprophylaxis, VTE-related maternal mortality remains at levels seen in the mid-1990s. As foundational work for an update of the current, 2015 RCOG guideline on VTE prevention in pregnancy and postpartum, we formally surveyed healthcare professionals in the UK. Over 90% of respondents felt confident using the guideline; but nevertheless more than one-third felt the current RCOG GTG-37a VTE risk scoring system is too complex, both antenatally and postnatally. Additional free-text responses emphasised the complexity of VTE risk assessment, and the need for simplification and specificity. Twenty-four percent of respondents overestimated the risk of developing VTE in pregnancy and postpartum, and 43% over-estimated the risk of dying from VTE. Also, clinicians felt a very high risk of developing VTE in pregnancy was needed to warrant thromboprophylaxis, with the average response suggesting a risk 50-times higher than the 10-20 per 10,000 baseline risk in pregnancy/postpartum. A challenge going forward is producing a simple and easy-to-use, evidence-based guideline that can facilitate shared-decision making and offer best clinical care.
No takes yet. Share an insight, caveat, or question.
Scott et al. (2026) conducted a cross-sectional in Pregnancy-related VTE risk assessment. Survey of VTE risk perception was evaluated on Perception of VTE risk and guideline complexity. A UK survey of healthcare professionals found that >33% felt the RCOG VTE risk scoring system is too complex, 24% overestimated VTE risk, and 43% overestimated the risk of dying from VTE.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: