Case series demonstrates early-onset seizures from peripartum hyponatraemia in neonates, highlighting the importance of maternal fluid balance monitoring.
Key Points
To highlight the critical role of maternal sodium homeostasis during labour and show how peripartum hyponatraemia leads to neonatal electrolyte disturbances and early seizures.
Analyzed the clinical presentation, labour course, biochemical parameters, and outcomes of 3 parturients and their neonates (N=3) presenting with significant hyponatraemia.
Maternal presentations varied widely, with one patient remaining asymptomatic, one exhibiting drowsiness under Entonox analgesia, and one developing generalized tonic-clonic seizures.
All three neonates experienced seizures on postnatal day 1 due to hyponatraemia, fully responded to intravenous saline, and showed normal neurodevelopmental outcomes alongside normal sepsis and calcium panels.