Key result
TTE-guided transcatheter ASD closure in children <15 kg achieves 94% procedural success.
Why the study?
Transcatheter ASD closure under transthoracic echocardiography guidance is performed at few centers and data in smaller children are scarce.
Does transcatheter device closure under transthoracic echocardiographic guidance achieve high procedural success and safety in children weighing less than 15 Kg with ostium secundum atrial septal defect?
Observational (n=83)
Does transcatheter device closure under transthoracic echocardiographic guidance achieve high procedural success and safety in children weighing less than 15 Kg with ostium secundum atrial septal defect?
Transcatheter closure of ostium secundum ASD under TTE guidance is safe and highly effective in children weighing less than 15 kg, achieving 100% occlusion at 3 months.
Answers are grounded in this paper and cite their sources.
May support TTE-guided closure in low-weight children; leaves open need for randomized trials to confirm safety.
Background: Transcatheter device closure of ostium secundum atrial septal defect is a safe & effective intervention in older children, & is usually done under transesophageal echocardiography guidance. However, the procedure under transthoracic echocardiography guidance, especially in smaller children, is done only at few centers, the data of which is scarce. Methods: A prospective study was undertaken to assess the mid-term efficacy and outcome of transcatheter device closure of ostium secundum atrial septal defect under transthoracic echocardiographic guidance, in children <15 Kg. Results: Eighty three children with ostium secundum atrial septal defect were included in the study. Median age of the study population was 3.5 years (1.9-5.6 years), and median weight of 11.6 Kg (7.6 - 14.9 Kg). The primary and secondary procedural success rates were 94% and 96.4% respectively. Post procedure patients were followed up for 12-30 months. Device related major complications were encountered in 4 (4.8%) cases. The total occlusion rates of the defect at 24 hours, 1 month and 3 months post procedure were 94%, 98.8% and 100% respectively. Conclusion: The transcatheter device closure of ostium secundum atrial septal defect under transthoracic echocardiography guidance, in children <15 Kg, has a high short and mid-term safety and efficacy.
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Arora et al. (2019) conducted an observational in Ostium secundum atrial septal defect (n=83). Transcatheter device closure under transthoracic echocardiographic guidance was evaluated on Primary procedural success. Transcatheter device closure of ostium secundum atrial septal defect under transthoracic echocardiographic guidance in children <15 Kg achieved a primary procedural success rate of 94%.
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