Penicillin Anaphylaxis Occurring in a Patient on Steroid Therapy

Case Reports1 December 1957PENICILLIN ANAPHYLAXIS OCCURRING IN A PATIENT ON STEROID THERAPYI. LEONARD BERNSTEIN, M.D., ALFRED LUSTBERG, M.D.I. LEONARD BERNSTEIN, M.D.Search for more papers by this author, ALFRED LUSTBERG, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-47-6-1276 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONIt is generally recognized that steroid therapy is very effective in the management of allergic states, but, on the other hand, the delayed responses of these substances at local tissue sites make them of only secondary value in the immediate treatment of anaphylactic episodes.1, 2Furthermore, there has been speculation as to whether previous cortical hormone therapy could actually prevent an anaphylactic reaction or a severe delayed reaction. The latter situation has already been described in a recent report from England3of a case in which a severe exfoliative dermatitis due to drugs was not prevented by full therapeutic...Bibliography1. FeinbergFeinberg SMAR: Allergy to penicillin, J. A. M. A. 160: 728 (Mar. 3) 1956. Google Scholar2. FitzgeraldIrvine JDAH: Use of cortisone and ACTH in serum sickness and penicillin reactions, Canad. M. A. J. 74: 46 (Jan. 1) 1956. MedlineGoogle Scholar3. McMurdoch JO: Severe drug hypersensitivity while under treatment with combined cortisone and chemotherapy for pulmonary tuberculosis, Brit. J. Tuberc. 49: 242 (July) 1955. CrossrefGoogle Scholar4. FrankelStutsman DBRE: Prophylaxis of penicillin reactions with Chlortrimeton injection, Ann. Allergy 13: 563-570 (Sept.-Oct.) 1955. MedlineGoogle Scholar5. MathewsHemphillLovellForsytheSheldon KPFMRGWEJM: A controlled study on the use of parenteral and oral antihistamines in preventing penicillin reactions, J. Allergy 27: 1 (Jan.) 1956. CrossrefMedlineGoogle Scholar6. KligmanEpstein AMWL: Suppression of local allergic reactions with hydrocortisone, J. Allergy 27: 395 (Sept.) 1956. CrossrefMedlineGoogle Scholar7. Tidwell TH: Penicillin anaphylactoid reaction successfully treated with adrenaline, Brit. M. J. 2: 721 (Sept. 17) 1955. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cincinnati, Ohio*Received for publication May 3, 1957.From the Department of Internal Medicine, Jewish Hospital, Cincinnati, Ohio.Requests for reprints should be addressed to Alfred Lustberg, M.D., 511 Doctors Building, 19 Garfield Place, Cincinnati 2, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAllergic Reactions to DrugsSPECIFIC HYPOSENSITIZATION OF PATIENTS WITH PENICILLIN ALLERGYSevere Vinblastine-Induced Leukopenia During Late Pregnancy with Delivery of a Normal InfantJAMES J. NORDLUND, M.D., VINCENT T. DEVITA, M.D., PAUL P. CABBONE, M.D.Treatment of Bacterial Endocarditis in Patients with Penicillin HypersensitivityGEORGE R. GREEN, M.D., GUSTAVUS A. PETERS, M.D., F.A.C.P., JOSEPH E. GERACI, M.D., F.A.C.P.BACTERIAL ENDOCARDITIS DUE TO NEISSERIA PERFLAVA IN A PATIENT HYPERSENSITIVE TO PENICILLINTreatment of Bacterial Endocarditis with Cephalosporin Derivatives in Penicillin-Allergic PatientsUse of Steroids in Penicillin-Sensitive Patients with Bacterial EndocarditisInfluence of Penicillin Allergic Reactions on Venereal Disease Control ProgrammesPenicillin Hypersensitivity in Patients with Bacterial EndocarditisMICHAEL H. GRIECO, M.D., MICHAEL R. DUBIN, M.D., JOHN L. ROBINSON, M.D., MILES J. SCHWARTZ, M.D., F.A.C.P.AnaphylaxisTETRACYCLINE PROVOCATION IN LUPUS ERYTHEMATOSUS*CASIMIR A. DOMZ, M.D., F.A.C.P., DELBERT H. MCNAMARA, M.D., F.A.C.P., HANS F. HOLZAPFEL, M.D. 1 December 1957Volume 47, Issue 6Page: 1276-1279KeywordsAllergy and immunologyAnaphylaxisDrugsHormonal therapyHormonesHospital medicinePenicillinSteroid therapy ePublished: 1 December 2008 Issue Published: 1 December 1957 PDF downloadLoading ...