The kidneys filter the plasma in special filtration units-glomeruli-and thereby excrete low-molecular-weight waste products into the urine. The mechanisms of glomerular filtration have been a matter of controversy for several decades, but recent data have revealed new details about the molecular nature of the filter and have demonstrated a central role for the podocyte slit diaphragm in the filtration process.
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Tryggvason et al. (2005) studied this question.
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