Key result
H1N1 infection presents with fully reversible neurological complications including seizures and altered mental status.
Why the study?
Pandemic influenza A (H1N1) 2009 can present with neurological manifestations, but reports of such atypical presentations are rare.
Case Report (n=6)
Pandemic influenza A (H1N1) 2009 can present with atypical neurological manifestations such as seizures or altered mental status, which appear to resolve without sequelae.
H1N1 may present with neurological features and resolve without sequelae; leaves open generalizability and need for prospective studies.
Please cite this paper as: Noriega et al. (2010) Pandemic influenza a (H1N1) 2009 with neurological manifestations, a case series. Influenza and Other Respiratory Viruses 4(3), 117–120. Objectives Describe a series of atypical presentations of pandemic influenza A (H1N1) 2009. Methods Description of case series using hospital records. Results Six patients aged 1 to 65 years with confirmed pandemic influenza A (H1N1) 2009 infection presented with neurological complications within 2 to 5 days after the first signs of influenza‐like illness. All six were admitted with seizures or altered mental status. No abnormalities were found in brain scans or cerebral spinal fluid studies of any of the six. All were discharged without sequelae within days of admission. Conclusions This is only the second report of pandemic influenza presenting with neurological manifestations. Clinicians caring for patients when pandemic influenza is prevalent in their communities should maintain a high level of awareness of the potential atypical presentations with which this disease can appear.
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Noriega et al. (2010) conducted a case report in Pandemic influenza A (H1N1) 2009 (n=6). Pandemic influenza A (H1N1) 2009 infection was evaluated on Neurological complications (seizures or altered mental status). Pandemic influenza A (H1N1) 2009 infection presented with neurological manifestations including seizures or altered mental status in 6 patients, all of whom were discharged without sequelae.
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