Neuroleptics are found in the 11‐amino substituted dibenzo[b,f]‐1, 4‐thiazepine and dibenzo[b,f]‐1, 4‐oxazepine series III. They may be synthesized by aminolysis of the iminochlorides VI and/or by Bischler‐Napieralski ring closure of the urea II with POCl3.
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Schmutz et al. (1967) studied this question.