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Introduction: Cannabis is the most commonly used illicit drug worldwide in adults. Several studies suggest an interaction of cannabis intake and anesthetic drugs like propofol and thiopental, but the pharmacodynamic interaction between cannabis and commonly used anesthetic drugs is still not well understood. Case Report: A 37-year- old male patient with a history of regular cannabis consumption and cannabis intake the day before surgery was admitted for an arthroscopic shoulder stabilization. Induction of anesthesia required large doses of propofol, thiopental and sevoflurane. Maintenance was achieved with the additional application of nitrous oxide to provide clinical tolerance of the surgical procedure. Return of consciousness and the postoperative course were uneventful. Conclusion: History of cannabis intake should be taken into routine preoperative assessment and patients should be closely monitored by experienced anesthesia staff for adequate anesthetic depth and analgesia.
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Richtig et al. (2015) studied this question.
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