Values of over 99 % ee were obtained for all the tested substrates in the RhI-catalyzed Alder-ene reaction, as applied to the highly enantioselective formation of functionalized lactams. In most cases, α-substituted γ-butyrolactams were obtained in high yields by simply mixing commercially available [{Rh(cod)Cl}2] and binap with the substrates (see scheme).
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Lei et al. (2002) studied this question.