Answers are grounded in this paper and cite their sources.
In order to analyze the mechanism of sex differentiation, fertilized eggs of Oryzias latipes with sex-linked R (orange-red) and r (white) phenotypes were exposed to estradiol-17β at various concentrations until hatching, and fry were reared on a normal diet up to sexual maturity. When embryos 0–6 days after fertilization were immersed in saline containing estradiol-17β at 1 μg/ml for only 4–10 days until hatching, the sex reversal of genotypic males to females was induced. The majority of the sex-reversed females (XrYR) were fertile, as indicated by the presence of vitellogenetic oocytes in their ovaries. These results show that steroid treatment during embryonic stages is a very convenient method for sex reversal in the medaka. J. Exp. Zool. 283:210–214, 1999.
No takes yet. Share an insight, caveat, or question.
Takashi Iwamatsu (1999) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: