Key result
Younger adults show a ~5 msec delay in anterior potential minimum during depolarization versus middle-aged adults.
Why the study?
Age-related differences in body surface potential maps of ventricular depolarization in normal adults were not well characterized.
Do body surface potential map parameters of ventricular depolarization differ between younger and middle-aged normal adults?
Cross-Sectional (n=50)
No
Do body surface potential map parameters of ventricular depolarization differ between younger and middle-aged normal adults?
Absolute Event Rate: 28.5% vs 23.3%
p-value: p=<0.001
Body surface potential maps show consistent patterns of ventricular depolarization in normal adults, but specific potential parameters differ significantly with age.
Age-specific norms may be needed for body surface potential mapping; leaves open whether differences affect diagnostic accuracy in younger adults.
Body surface potential maps were obtained in 50 normal adults using the heart potential map system designed by Yamada. Group A (younger adult group) consisted of 30 persons whose ages ranged from 20 to 39 years. Group B (middle-aged group) included 20 persons whose ages ranged from 40 to 59 years. Although there were slight variations in the pattern of isopotential distribution among the subjects studied, a consistent pattern with a similar sequence was observed in both study groups. However, there were some parameters which significantly differed between groups A and B, including the earliest appearance time of the anterior negative potential (p < 0.05), the anterior potential minimum (p < 0.001), the posterior positive potential (p < 0.001), the midsternal minimum (p < 0.001), the largest potential minimum (p < 0.05), the largest potential maximum (p < 0.005), the "reversal" pattern (p < 0.001), the multipolar potential distribution in the upstroke (p < 0.001) and the amplitude of potential minimum in the periods 50 msec (p < 0.005) and 60 msec (p < 0.01) of ventricular depolarization. Accordingly, the data obtained regarding the time relationship between the bipolar and multipolar phases, the distribution and time course of the potential as well as the dynamic changes in potential voltage, particularly the age-related potential pattern will serve as a basis for further study of BSPM.
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Tseng et al. (1993) conducted a cross-sectional in Healthy adults (n=50). Younger age (20-39 years) vs. Middle age (40-59 years) was evaluated on Earliest appearance time of the anterior potential minimum (msec) (p=<0.001). Younger adults aged 20-39 years exhibited significantly delayed appearance of the anterior potential minimum (28.5 vs 23.3 msec, p<0.001) during ventricular depolarization compared to adults aged 40-59 years.
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