New enzymatic methods for the synthesis of primary α-aminonitriles and unnatural α-amino acids by oxidative cyanation of primary amines with d -amino acid oxidase from porcine kidney

This is the authors' abstract. We don't add key points for this paper.

Oxidation of amino groups in amines or amino acids activates the sp 3 C α –H bond to form imines, making the alpha carbon atom a preferable target for nucleophilic reagents such as cyanide.