Key result
Asian CAD patients show more severe angiographic disease than white peers despite fewer traditional risk factors.
Why the study?
Does Asian ethnicity compared to white ethnicity affect the pattern and severity of coronary artery disease in matched patients?
Observational (n=102)
Blind assessment
Does Asian ethnicity compared to white ethnicity affect the pattern and severity of coronary artery disease in matched patients?
Asian patients with CAD have more severe angiographic disease than matched white patients, despite having a more favorable traditional risk factor profile.
May inform ethnicity-adjusted CAD risk assessment; leaves open mechanisms and prospective validation.
Thirty-four Asian patients with coronary artery disease (CAD) were each matched for age, sex, blood pressure and duration of symptoms with 2 white patients with CAD. Blind assessment of coronary arteriograms demonstrated significantly more severe disease in Asians but distribution of disease was similar in both groups. Assessment of risk factors showed that the Asian group had significantly more non-smokers, lower cholesterol levels and weighed less than whites.
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Lowry et al. (1983) conducted an observational in Coronary artery disease (n=102). Asian ethnicity vs. White ethnicity was evaluated on Severity and distribution of coronary artery disease on arteriograms. Asian patients with coronary artery disease had significantly more severe disease on coronary arteriograms compared to matched white patients, despite having fewer traditional risk factors.
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