Pafolacianine: A Diagnostic Agent to Identify Lung Cancer Lesions in Adults with Known or Suspected Lung Cancer

Accurately detecting lung tumours and their margins is important for disease outcomes.1,2 However, detection is challenging due to the use of minimally invasive surgery and current localization techniques, such as computed tomography (CT)-guided and endobronchial interventions, which add significantly to procedure time and risk of complications. 3 Intraoperative imaging using a targeted agent to optically fluoresce cancerous cells may address these problems, in addition to locating previously unknown tumours and determining tumour margins.4