Key result
ECMO successfully rescues 3 children with progressive refractory near-fatal asthma.
Why the study?
Data on outcomes in children requiring extracorporeal membrane oxygenation support for status asthmaticus is sparse.
Does extracorporeal membrane oxygenation (ECMO) improve survival in children with life-threatening refractory asthma?
Case Report (n=3)
Does extracorporeal membrane oxygenation (ECMO) improve survival in children with life-threatening refractory asthma?
ECMO can be successfully used as a rescue therapy for children with refractory near-fatal asthma.
May support ECMO rescue consideration in refractory pediatric asthma; leaves open survival benefit in larger cohorts.
Progressive refractory near-fatal asthma requiring intubation and mechanical ventilation can lead to death. Data on outcomes in children requiring extracorporeal membrane oxygenation (ECMO) support for status asthmaticus is sparse. We describe our experience of three patients in the winter of 2018 to 2019 successfully rescued with ECMO. We also report our novel use of extubation while still being on ECMO support. Awareness and use of ECMO in refractory asthma can help lower the mortality for this very common disease in children. We also review the current literature on the use of ECMO and other extracorporeal therapies in asthma.
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Medar et al. (2019) conducted a case report in Life-threatening asthma (n=3). Extracorporeal membrane oxygenation (ECMO) was evaluated on Successful rescue. Extracorporeal membrane oxygenation (ECMO) successfully rescued three children with progressive refractory near-fatal asthma.
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