Key result
Case report links influenza-associated pneumonia to severe acute arterial and venous thrombotic events.
Case Report (n=1)
Influenza-associated pneumonia can be complicated by severe acute thrombotic vascular events, including DVT, PE, and arterial embolism, necessitating clinical vigilance.
Thrombotic complications may occur in influenza pneumonia; leaves open whether prophylaxis improves outcomes.
A 58-year-old man with previous myocardial infarction presented to our hospital with fever, cough, and dyspnea. PCR testing with nasopharyngeal swabs confirmed influenza virus infection, and enhanced computed tomography and transthoracic echocardiography revealed bilateral ground-glass opacities and consolidation, deep venous thrombosis, acute pulmonary artery embolism, and acute arterial embolism that appeared to originate from thrombus in the left ventricle. Combination of a neuraminidase inhibitor, antibiotics, an anticoagulant, and anti-platelet agent improved these complications; however, amputation of the patient's right foot was required. Because influenza can cause vascular events, physicians should pay attention to this complication in patients with influenza-associated pneumonia.
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Ishiguro et al. (2019) conducted a case report in Influenza-associated pneumonia with acute thrombotic vascular events (n=1). Influenza virus infection was evaluated. Influenza-associated pneumonia in a 58-year-old man was complicated by severe acute thrombotic vascular events, including deep venous thrombosis, pulmonary embolism, and arterial embolism.
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