A Short Efficient Synthesis of 11-Monoacetate of Drimane-8α,11-diol from Norambreinolide

All articles of this category An efficient two-step synthesis of 11-acetoxydrimane-8 α -ol, a valuable intermediate for the synthesis of naturally occurring drimanes, from commercially available norambreinolide, is described. The Baeyer-Villiger oxidation of the initially obtained 8 α -hydroxy-12-oxo-11-homodrimane is considered as the key step. oxidation