Integrins are heterodimeric plasma membrane glycoproteins involved in cell-matrix and cell-cell interactions. The present communication reviews the distribution of several of the currently known integrin subunits in the corneal epithelium. The corneal epithelium contains the following integrin heterodimers: alpha 2 beta 1, alpha 3 beta 1, and alpha 6 beta 4. The expression of alpha v with an unknown beta subunit is also recognized, whereas the expression of alpha 4 and alpha 5 subunits remains controversial. Some of the changes occurring in the distribution of integrins in response to wounding will also be discussed.
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Päällysaho et al. (1992) studied this question.
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