Key result
IV oxycodone lowers postoperative pain scores vs morphine after laparoscopic cholecystectomy.
Why the study?
Visceral pain frequently leads patients to seek medical attention after laparoscopic surgery, prompting an evaluation of intravenous oxycodone versus morphine on postoperative pain after laparoscopic cholecystectomy.
Does intravenous oxycodone reduce postoperative pain compared to intravenous morphine in patients undergoing laparoscopic cholecystectomy?
RCT (n=50)
Single-blind
randomized
No
Does intravenous oxycodone reduce postoperative pain compared to intravenous morphine in patients undergoing laparoscopic cholecystectomy?
Intravenous oxycodone provides superior postoperative analgesia with less need for additional analgesia compared to morphine after laparoscopic cholecystectomy.
Supports preferring oxycodone for post-laparoscopic cholecystectomy analgesia; extends RCT evidence on opioid choice in minimally invasive surgery.
Background: one of common causes studied cases that seek medical attention after laparoscopic surgery is visceral pain. Opioids are commonly used analgesics for postoperative visceral pain because they can be utilized either before & after surgery in a patient-controlled analgesia pump. Aim of the Work: Intravenous oxycodone versus morphine after laparoscopic cholecystectomy on postoperative pain: the primary result is to compare the impacts of the severity of postoperative pain using VAS score. The secondary outcomes are to compare occurrence of postoperative nausea, & vomiting, impact on HR, & length of hospital stay. Patients & Techniques: This study was prospective, single-blinded, and controlled randomized research conducted at Al-Azhar University Hospitals, Following the patient's informed consent, 50 patients undergoing laparoscopic cholecystectomy creation of the following criteria were conducted for this study from April 2022 to October 2022. Results: A 0–10 visual analog scale (VAS) was utilized to measure the postoperative pain. Was larger in Morphine group compared to oxycodone group with p-value Conclusion: Oxycodon has a good postoperative analgesic effect with less need for postoperative analgesia, which can be a good alternative to Morphine.
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Sabra et al. (2023) conducted an RCT in Postoperative pain after laparoscopic cholecystectomy (n=50). Intravenous oxycodone vs. Intravenous morphine was evaluated on Severity of postoperative pain using VAS score. Intravenous oxycodone resulted in lower postoperative pain scores on the visual analog scale compared to morphine in patients undergoing laparoscopic cholecystectomy.
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