Lamotrigine-Induced Neutropenia

general (3).However, the use of antipsychotics in catatonia treatment is a contentious issue, given reports that high potency antipsychotics precipitated or exacerbated catatonia or neuroleptic malignant syndrome (NMS), a variant of malignant catatonia (3).In this regard, some authors suggest adjunctive use of a benzodiazepine while the antipsychotic drugs are being introduced, in the hope that a benzodiazepine may reduce the risk of NMS (6).We cannot ascertain whether this patient would have responded to higher dosages of lorazepam.However, the dosage this patient received is in the range used by other investigators to treat catatonia (2).While benzodiazepines, ECT, or atypical antipsychotics have been used to treat the acute phase of periodic catatonia, more research is needed on the duration of treating the acute phase with these modalities, as well as on the treatment of interepisode residual symptoms.