TFAP2A enhances tumor stemness and promotes metastasis in pancreatic ductal adenocarcinoma

This is the authors' abstract. We don't add key points for this paper.

. Mechanistically, TFAP2A could promote epithelial mesenchymal transition (EMT) and recruit macrophage by upregulating MYC, facilitating PDAC cell intravasation. Collectively, these findings unveil molecular mechanisms for PDAC liver metastasis and potential therapeutic targets.