Educational Case: Unraveling chronic recurrent multifocal osteomyelitis: An autoinflammatory bone disorder

Luke Passannante; Laleh Hakima

doi:10.1016/j.acpath.2026.100286

August 7, 2026Academic PathologyOpen Access

Educational Case: Unraveling chronic recurrent multifocal osteomyelitis: An autoinflammatory bone disorder

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Key Points

To review the pathogenesis, predisposing factors, causal organisms, morphological characteristics, and complications associated with osteomyelitis and septic arthritis.
Structured an educational curriculum case module aligned with medical learning objective MS2.2.
Synthesized pathophysiologic mechanisms, histopathologic features, and clinical distinctions between infectious and autoinflammatory bone pathologies.
Delineates the clinical presentation and sterile autoinflammatory etiology underlying chronic recurrent multifocal osteomyelitis.
Categorizes common microbial pathogens, predisposing risk factors, and structural complications seen in infectious osteomyelitis and septic arthritis.

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Implication

Educational review reveals the pathogenesis and morphology of osteomyelitis and septic arthritis in clinical pathology, highlighting key diagnostic features of autoinflammatory disorders.

Abstract

Primary objectiveObjective MS2.2: Osteomyelitis and Septic Arthritis.Discuss the pathogenesis of osteomyelitis and septic arthritis, including predisposing factors, organisms involved, morphologic appearance, and complications.

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Cite This Study

Passannante et al. (2026) studied this question.

synapsesocial.com/papers/6aa954b1f4090451fe46285f https://doi.org/10.1016/j.acpath.2026.100286

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Educational Case: Unraveling chronic recurrent multifocal osteomyelitis: An autoinflammatory bone disorder

Key Points

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Implication

Abstract

Discussion

Cite This Study

Educational Case: Unraveling chronic recurrent multifocal osteomyelitis: An autoinflammatory bone disorder

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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